What is Safety Pharmacology?

Safety Pharmacology is a component of the preclinical/nonclinical drug development process. As new chemical, biological, or molecular entities are discovered, it is important to evaluate these therapeutics for safety. Safety Pharmacology evaluates new therapeutics for potential "off-target" adverse events in critical organ systems (e.g. central nervous system, cardiovascular system and respiratory system) at therapeutic dosing levels. These studies, along with Drug Toxicology safety assessments, are required by the FDA prior to dosing in humans (i.e Clinical Trials). Pharmacologists and Drug Toxicologists play a critical role in developing safe and effective drugs. The Applied Pharmacology & Drug Toxicology MS program trains students in preclinical/nonclinical drug safety by exploring Principles of Safety Pharmacology, Drug Toxicology, and Good Laboratory/Manufacturing/Clinical Practices.  In addition, regulatory requirements, including ICH guidelines, are integrated throughout the curriculum.