Welcome to the McCullumsmith Lab

Cognitive Disorders Research Laboratory

The Cognitive Disorders Research Laboratory (CDRL) is located in the Department of Psychiatry and Behavioral Neuroscience at the University Of Cincinnati College Of Medicine. The mission of the CDRL is to explore the pathophysiology of neuropsychiatric disorders with marked cognitive deficits. The laboratory is currently focused on testing specific hypotheses related to schizophrenia and traumatic brain injury. We hypothesize that changes in glutamate reuptake are altered in both of these illnesses, reflecting abnormalities of the expression, localization, and function of glutamate transporters. Robert McCullumsmith, MD/PhD and Principle Investigator of the laboratory, is a board certified psychiatrist who sees patients at the Cincinnati VAMC, and at the Stetson clinic at the University of Cincinnati. Dr. McCullumsmith’s overarching goal is to ask and answer the largest possible questions in translational neuroscience, using a combination of human postmortem brain tissues and animal models to test specific hypotheses related to the pathophysiology of disease.